1962-1971: 19 million gallons of defoliating herbicides were dropped by U.S. personnel over 10-20% of Vietnam and parts of Laos.

Agent Orange was the most frequently used defoliating agent. The use of this chemical was controversial both because of fears for those handling it, as well as those being sprayed with it.

Reports of malformed babies began in the 1970's in the areas sprayed by the defoliant.